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Mesotherapy vs Microneedling: Which is Right For You?

We understand that the options available to you can often feel overwhelming regarding skincare and aesthetic treatments. When it comes to skin revitalisation, however, our patients often ask us about one of two treatments: mesotherapy vs microneedling. Both mesotherapy and microneedling are minimally invasive treatments that restore healthier, younger-looking skin. Although they both involve the use of microscopic needles, they are some essential differences to be aware of. Each offers unique benefits, but understanding how they differ is crucial when choosing a treatment to add to your beauty regime. 

In this article, we’ll delve into the practical differences between mesotherapy and microneedling, which you should choose depending on your skin concerns and how your treatment plan may look. At the end of this article, you’ll have the knowledge to decide between mesotherapy and microneedling. 





Mesotherapy is a non-surgical cosmetic treatment that rejuvenates the skin by injecting a custom-made medical cocktail – or as we like to call it, the Mesolift cocktail. This bespoke Mesolift cocktail can be customised to suit your skin needs, but usually contains hyaluronic acid, vitamins, antioxidants, and amino acids. This cocktail is delivered directly into the mesoderm, aka the middle layer of your skin. This results in increased collagen and elastin, improved blood circulation, and flushing out of ageing toxins. The visible effects of mesotherapy are improved appearance of superficial wrinkles, reduction in skin pigmentation, and restoration of youthful skin glow.

The first step in mesotherapy treatment is a consultation and skin examination with one of our specialist doctor aestheticians. Once your custom Mesolift cocktail and treatment plan is agreed upon, we can begin immediately. First, we clean the skin and apply a numbing cream for comfort. Then, we use an air-pressure gun to administer the injections. The device allows us to deliver an equal micro-dose of the Mesolift cocktail via a microneedle. A soothing, hydrating hyaluronic acid mask is applied at the end of the treatment for an extra boost of nutrients. After a short rest you’re free to go and can go about your normal daily activities with no downtime. 

Few people realise it, but mesotherapy can be performed on many skin areas. Specifically, we perform facial mesotherapy, body mesotherapy, and hair mesotherapy for hair loss at Dr Dray. Each treatment has a unique Mesolift cocktail and is targeted to address a specific skin concern in the relevant body area. 

No matter where on the body you choose to have mesotherapy, we recommend regular maintenance treatments for longer-lasting results.


Mesotherapy for hair



Microneedling, on the other hand, does not involve injecting anything into the skin. Instead microneedling uses small needles to create tiny micro-wounds in the skin. The way microneedling works is to stimulate your body’s immune system. Doing so triggers a wound-healing process which encourages replacing old skin with new youthful skin full of collagen and elastin. The visual effect of this is improved skin tightness, improved appearance of scars and fine lines, and improved skin tone and texture. 

Similar to mesotherapy, you would first have a consultation with one of our specialist doctors and agree on a plan. After, a numbing cream is applied, and the procedure is performed as described above. Microneedling treatments typically last between 20 to 30 minutes. The skin can appear slightly red or swollen immediately after the treatment, but do not worry, this is normal and usually settles within minutes to hours. Overall there’s little downtime with microneedling. 


Mesotherapy vs Microneedling: Which to Choose?

When choosing between mesotherapy and microneedling, consider your skin concerns and goals. Mesotherapy is an excellent choice for those seeking a targeted solution for a specific skin concern, for example, dull skin, superficial wrinkles or hair loss. And more generally, it offers excellent deep revitalisation and hydration of the skin. 

Microneedling, on the other hand, is better suited for people looking to reduce scars/wrinkles and who do not want anything injected into their skin. 


Our Recommendation

Both mesotherapy and microneedling are proven methods to rejuvenate and revitalise the skin. The choice between the two ultimately comes down to your skin type and goals. However, mesotherapy comes out as the superior treatment overall in our opinion. The reason we believe mesotherapy is best for most people is that you get the same wound-healing response with mesotherapy, as you do with microneedling. But you also get the profound benefits of a nourishing and hydrating Mesolift cocktail full of vitamins and minerals.

At Clinic Dr Dray, our Mesotherapy treatments are performed by specialist doctors using only the highest-quality products. Please do not hesitate to contact us at our London branch

Our team of skilled doctors at Clinic Dr Dray London are dedicated to helping you achieve your aesthetic goals and addressing your unique concerns. We invite you to book a consultation.

If you would like to book a consultation please use the form below or email – info@drdray.co.uk